REFRACTORY PERIOD OF SINGLE MOTOR-NERVE FIBERS IN MAN
REFRACTORY PERIOD OF SINGLE MOTOR-NERVE FIBERS IN MAN
复制标题
DOI：
10.1136/jnnp.47.4.344
复制
发表时间：
1984-01-01
影响因子：
11
通讯作者：
BORG, J
中科院分区：
文献类型：
--
作者：
BORG, J
采用单运动单位肌电图记录法，对28个正常青年人副神经支配的运动单位和10个老年人再支配的运动单位的轴突不应期进行了研究。不应期测量后，条件反射逆行传播神经冲动和后，通过相同的电极作为测试刺激传递的条件电神经刺激。传播脉冲后的不应期为1.83 ± 0.01。0.26当测试刺激强度在静息时高于轴突阈值10%时为0.88 ± 0.5ms，当测试刺激强度在静息时高于轴突阈值10%时为0.88 ± 0.5ms。0.26当测试刺激强度超过阈值100%时，为ms。电刺激后的相应数据为2.38 ± 0.01。0.32 ms和1.28 ±。0.22方法之间的差异部分是由于刺激传播的影响时，测量不应期后，逆向传播的神经冲动。神经纤维膜和周围组织在神经冲动传播后和电刺激后的不同性质也可能起作用。对于运动单位病理学的进一步研究，这两种方法似乎同样可靠时，适当的正常数据。
Electromyographic single motor unit recordings were used to study the axonal refractory period of 28 accessory nerve innervated motor units in young normal subjects and 10 reinnervated motor units in elderly subjects. The refractory period was measured after a conditioning antidromic propagated nerve impulse and after a conditioning electrical nerve stimulus delivered through the same electrode as the test stimulus. The refractory period after a propagated impulse was 1.83 .+-. 0.26 ms when test stimulus strength was 10% above the axonal threshold at rest and 0.88 .+-. 0.26 ms when test stimulus strength was 100% above threshold. Corresponding data after an electrical stimulus were 2.38 .+-. 0.32 ms and 1.28 .+-. 0.22 ms. The difference between the methods was partially due to the effect of stimulus spread when the refractory period was measured after an antidromic propagated nerve impulse. Different properties of the nerve fiber membrane and the surrounding tissues after a propagated nerve impulse and after an electrical stimulus might also contribute. For further studies of motor unit pathology both methods seem equally reliable when proper normal data are available.