Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study Group
Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study Group
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DOI：
10.1016/j.jamda.2013.05.021
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发表时间：
2013-08-01
影响因子：
7.6
通讯作者：
Boirie, Yves
中科院分区：
文献类型：
--
作者：
Bauer, Juergen;Biolo, Gianni;Boirie, Yves
新的证据表明，老年人比年轻人需要更多的饮食蛋白质来支持良好的健康，促进疾病的恢复，并维持功能。老年人需要弥补与年龄相关的蛋白质代谢变化，如内脏提取率高和对摄入蛋白质的合成代谢反应下降。他们还需要更多的蛋白质来抵消与慢性和急性疾病相关的炎症和分解代谢状况，这些疾病通常随着年龄的增长而发生。为了制定老年人最佳蛋白质摄入量的最新循证建议，欧洲联盟老年医学会(EUGMS)与其他科学组织合作，任命了一个国际研究小组(Prot-AGE研究小组)来审查与老龄化有关的饮食蛋白质需求。为了帮助老年人(65岁)保持和恢复苗条的身体质量和功能，保护年龄研究小组建议平均每天摄入量至少在每公斤体重1.0至1.2克蛋白质的范围内。耐力型和抵抗型运动都建议在安全和耐受的个性化水平上进行，建议正在锻炼或从事其他活动的人摄入更高的蛋白质(即1.2g/kg体重/d)。大多数患有急慢性疾病的老年人需要更多的膳食蛋白质(即1.2-1.5克/公斤体重/天)。患有严重肾脏疾病的老年人(即，估计的GFR
New evidence shows that older adults need more dietary protein than do younger adults to support good health, promote recovery from illness, and maintain functionality. Older people need to make up for age-related changes in protein metabolism, such as high splanchnic extraction and declining anabolic responses to ingested protein. They also need more protein to offset inflammatory and catabolic conditions associated with chronic and acute diseases that occur commonly with aging. With the goal of developing updated, evidence-based recommendations for optimal protein intake by older people, the European Union Geriatric Medicine Society (EUGMS), in cooperation with other scientific organizations, appointed an international study group to review dietary protein needs with aging (PROT-AGE Study Group). To help older people (>65 years) maintain and regain lean body mass and function, the PROT-AGE study group recommends average daily intake at least in the range of 1.0 to 1.2 g protein per kilogram of body weight per day. Both endurance-and resistance-type exercises are recommended at individualized levels that are safe and tolerated, and higher protein intake (ie, >= 1.2 g/kg body weight/d) is advised for those who are exercising and otherwise active. Most older adults who have acute or chronic diseases need even more dietary protein (ie, 1.2-1.5 g/kg body weight/d). Older people with severe kidney disease (ie, estimated GFR