Inhibition of influenza A virus sialidase activity by sulfatide
Inhibition of influenza A virus sialidase activity by sulfatide
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DOI：
10.1016/s0014-5793(03)01045-7
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发表时间：
2003-10-23
期刊：
影响因子：
3.5
通讯作者：
Suzuki, Y
中科院分区：
文献类型：
--
作者：
Suzuki, T;Takahashi, T;Suzuki, Y
Sulfatide, which binds to influenza A viruses and prevents the viral infection, was found to inhibit the sialidase activities of influenza A viruses in a pH-dependent manner. The kinetic parameters of the effect of sulfatide on the sialidase activities of human influenza A viruses using fluorometric assay indicated that sulfatide was a powerful and non-competitive type inhibitor in low-pH conditions. (C) 2003 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
