Engineering phosphorus metabolism in plants to produce a dual fertilization and weed control system
Engineering phosphorus metabolism in plants to produce a dual fertilization and weed control system
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DOI：
10.1038/nbt.2346
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发表时间：
2012-09-01
影响因子：
46.9
通讯作者：
Herrera-Estrella, Luis
中科院分区：
文献类型：
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作者：
Lizbeth Lopez-Arredondo, Damar;Herrera-Estrella, Luis
作物高产取决于持续投入的正磷酸盐（PO 4 -3）为基础的肥料和除草剂（1，2）。农业面临的两个主要挑战是磷是不可再生资源，杂草已经产生了广泛的除草剂抗性（3-5）。克服这两个问题的一个策略是改造植物，使其在竞争有限资源时胜过杂草和微生物，从而减少对肥料和除草剂的需求。植物和大多数微生物不能代谢亚磷酸盐（PO 3 -3），因此我们通过产生可以使用亚磷酸盐作为唯一磷源的转基因植物来开发双施肥和杂草控制系统。在温室条件下，当用亚磷酸盐施肥时，这些转基因植物需要少30-50%的磷输入，以达到与使用正磷酸盐肥料的相同植物获得的生产力相似的生产力，并且当与杂草竞争时，积累比用正磷酸盐施肥时大2-10倍的生物量。
High crop yields depend on the continuous input of orthophosphate (PO4-3)-based fertilizers and herbicides(1,2). Two major challenges for agriculture are that phosphorus is a nonrenewable resource and that weeds have developed broad herbicide resistance(3-5). One strategy to overcome both problems is to engineer plants to outcompete weeds and microorganisms for limiting resources, thereby reducing the requirement for both fertilizers and herbicides. Plants and most microorganisms are unable to metabolize phosphite (PO3-3), so we developed a dual fertilization and weed control system by generating transgenic plants that can use phosphite as a sole phosphorus source. Under greenhouse conditions, these transgenic plants require 30-50% less phosphorus input when fertilized with phosphite to achieve similar productivity to that obtained by the same plants using orthophosphate fertilizer and, when in competition with weeds, accumulate 2-10 times greater biomass than when fertilized with orthophosphate.