Determination of effective orifice area in mitral stenosis from non-invasive ultrasound Doppler data and mitral flow rate.
Determination of effective orifice area in mitral stenosis from non-invasive ultrasound Doppler data and mitral flow rate.
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根据无创超声多普勒数据和二尖瓣流速确定二尖瓣狭窄的有效孔口面积。
作者：
J. Holen;R. Aaslid;K. Landmark;S. Simonsen;T. Ostrem
对10例二尖瓣狭窄但无二尖瓣关闭不全的患者进行了心导管检查。超声、测压和直接Fick法分别测定二尖瓣口血流速度、二尖瓣压力梯度和二尖瓣血流速度。根据超声数据和二尖瓣血流速度计算有效瓣口面积。几何开口面积是根据压力梯度和二尖瓣血流速度，使用修正的Gorlin公式计算的。两种方法的比较显示，相关系数为0.975。研究表明，超声方法是二尖瓣血流阻塞定量的常规插管方法的替代方法。
Ten patients with mitral stenosis, but without mitral insufficiency, have been studied during cardiac catheterization. The mitral orifice blood velocities, the mitral pressure gradient, and the mitral flow rate were determined with ultrasound, manometry, and the direct Fick method, respectively. The effective orifice area was calculated from the ultrasound data and the mitral flow rate. The geometric orifice area was calculated from the pressure gradient and the mitral flow rate, using a revised Gorlin formula. A comparison of the two methods showed a correlation coefficient of 0.975. The investigation demonstrated that the ultrasound method represents an alternative to the conventional catheterization methods used for the quantification of mitral flow obstruction.