COMPUTER-AIDED RECONSTRUCTION OF NEURON TREES FROM SEVERAL SERIAL SECTIONS
COMPUTER-AIDED RECONSTRUCTION OF NEURON TREES FROM SEVERAL SERIAL SECTIONS
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DOI：
10.1016/0010-4809(77)90017-9
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发表时间：
1977-01-01
期刊：
影响因子：
--
通讯作者：
CAPOWSKI, JJ
中科院分区：
文献类型：
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作者：
CAPOWSKI, JJ
计算机辅助神经元树重建允许解剖学家在空间上可视化和统计总结树分支模式。跨越几个连续组织切片的树提出了一个困难的重建问题。来自不同部分的树木片段分别用计算机化显微镜相对于恒定的组织起源进行追踪。在计算机的帮助下，截面相对于该原点对齐。可以显示各个树段，并强调可能的合并点。在树原点选择不当的那些线段上执行树线段的转置。通过将树段的起点合并到其他树段的切割端来生成完整的重建。重建的树可以以平滑的旋转和平移来显示;也可以统计地汇总。[Cat在本研究中使用脊髓切片。
Computer-aided neuron tree reconstruction allows an anatomist to spatially visualize and statistically summarize the tree branching pattern. Trees which span several serial tissue sections present a difficult reconstruction problem. Segments of trees from different sections are traced separately with a computerized microscope relative to a constant tissue origin. With computer aid, sections are aligned with respect to this origin. Individual tree segments can be displayed with possible merging points emphasized. Transposition of tree segments is performed on those segments whose tree origin was improperly selected. Complete reconstructions are generated by merging origins of tree segments into cut ends of other tree segments. The reconstructed tree may be displayed with smooth rotation and translation; also it may be statistically summarized. [Cat spinal cord sections were used in this study.].