Hypothermia as a risk factor for pediatric cardiothoracic surgical site infection
Hypothermia as a risk factor for pediatric cardiothoracic surgical site infection
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DOI：
10.1097/00006454-200104000-00023
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发表时间：
2001-04-01
影响因子：
3.6
通讯作者：
Todd, JK
中科院分区：
文献类型：
--
作者：
McAnally, HB;Cutter, GR;Todd, JK
为了调查深低温是否与小儿心胸外科手术部位感染相关，我们进行了一项回顾性研究，评估了许多被认为与术后伤口感染相关的变量。最低核心体温是与感染风险增加最密切相关的临床因素，也是多变量分析中的唯一控制因素。尽管已报道了成人心胸外科手术部位感染的许多危险因素，但专门针对儿科此类感染的研究很少，而且儿科危险因素的特征还不明确。 2, 3 儿科和成人心胸手术的一个主要区别是在儿科病例中使用深低温。当灌注显着减少甚至停止以实现干燥的手术区域时，低温可通过降低组织需氧量来防止缺血性损伤。
To investigate whether deep hypothermia is associated with pediatric cardiothoracic surgical site infection, we performed a retrospective study evaluating many variables thought to be related to postoperative wound infection. Lowest core body temperature was the clinical factor most strongly associated with increased risk of infection and was the sole controlling factor in a multivariate analysis.Although many risk factors have been reported for cardiothoracic surgical site infections in adult populations, 1 studies specific to such infections in pediatrics are scarce, and pediatric risk factors are not as well-characterized. 2, 3 A major difference between pediatric and adult cardiothoracic surgery is the use of deep hypothermia in pediatric cases. Hypothermia protects against ischemic damage by lowering tissue oxygen demands during a time when perfusion is significantly reduced or even halted to allow for a dry operating field.