Endometrioid adenocarcinoma with squamous differentiation arising from ureteral endometriosis in a patient with no history of gonadal endometriosis.
Endometrioid adenocarcinoma with squamous differentiation arising from ureteral endometriosis in a patient with no history of gonadal endometriosis.
复制标题
无性腺子宫内膜异位症病史的患者因输尿管子宫内膜异位症引起的鳞状分化子宫内膜样腺癌。
DOI：
10.1016/j.ygyno.2005.06.056
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发表时间：
2005
影响因子：
4.7
通讯作者：
G. Scambia
中科院分区：
文献类型：
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作者：
M. Salerno;V. Masciullo;A. Naldini;G. Zannoni;V. Vellone;G. Scambia
背景：高达1%的子宫内膜异位症患者可能发生恶性转化，其中只有20%的病例发生在输卵管外盆腔部位。同样，尿路子宫内膜异位症也很少见，仅占所有子宫内膜异位症病变的1%。casan子宫内膜样癌伴鳞状分化，起源于输尿管周围子宫内膜异位症，表现为包裹右输尿管的盆腔肿块。患者于8年前因双侧浆液性良性囊肿伴右侧出血性黄体及子宫肌瘤行全子宫切除术及双侧输卵管卵巢切除术，并接受无对抗性雌激素替代治疗5年。结论：这是第二例子宫内膜异位症引起的恶性肿瘤，表现为输尿管梗阻性肿块，也是第一例子宫内膜异位症与性腺起源不一致的患者。对病例和相关文献进行分析，并讨论可能的发病机制。
BACKGROUNDMalignant transformation may occur in up to 1% of women with endometriosis and only 20% of these cases occur at extragonadal pelvic sites. Similarly, urinary tract endometriosis is rare and occurs in only 1% of all endometriotic lesions.CASEAn endometrioid carcinoma with squamous differentiation arising from periureteral endometriosis presented as a pelvic mass encasing the right ureter. The patient had a history of total hysterectomy and bilateral salpingo-oopherectomy 8 years earlier because of bilateral serous benign cysts with right hemorrhagic corpus luteum and uterine fibroids, and has since been under unopposed estrogen replacement therapy for 5 years.CONCLUSIONThis is the second case of a malignancy arising in endometriosis presenting as an obstructive ureteral mass and the first case of a patient with this condition whose endometriosis is not consistent with a gonadal origin. An analysis of the case and related literature is presented together with the discussion of possible pathogenetic mechanisms.
化学32（12）（1977）。
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