BIACORE J: a new platform for routine biomolecular interaction analysis

BIACORE J: a new platform for routine biomolecular interaction analysis
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DOI:
10.1002/jmr.535
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发表时间:
2001-07-01
影响因子:
2.7
通讯作者:
Myszka, DG
Myszka, DG
中科院分区:
生物学4区
文献类型:
--
作者:
Rich, RL;Myszka, DG

文献摘要

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SPR生物传感器技术不断发展。Biacore AB(瑞典乌普萨拉)最近发布的平台BIACORE J旨在用于生物分子相互作用的常规分析。使用抗体-蛋白A和配体-受体系统,我们证明了BIACORE J在确定活性浓度和结合亲和力中的实用性。这些研究的结果说明了仪器的高灵敏度及其产生可重现结合反应的能力。BIACORE J易于操作,适用于各种应用,使SPR技术作为研究工具广泛使用。版权所有(C)2001约翰威利父子有限公司
SPR biosensor technology continues to evolve. The recently released platform from Biacore AB (Uppsala, Sweden), BIACORE J, is designed for the routine analysis of biomolecular interactions. Using an antibody-protein A and a ligand-receptor system, we demonstrate the utility of BIACORE J in determining active concentration and binding affinities. The results from these studies illustrate the high sensitivity of the instrument and its ability to generate reproducible binding responses. The BIACORE J is easy to operate and useful in diverse applications, making SPR technology widely accessible as a research tool. Copyright (C) 2001 John Wiley & Sons, Ltd.