Membrane particle aggregates in innervated and noninnervated cultures of Xenopus embryonic muscle cells.

Membrane particle aggregates in innervated and noninnervated cultures of Xenopus embryonic muscle cells.
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非洲爪蟾胚胎肌细胞的受神经支配和非神经支配培养物中的膜颗粒聚集。

DOI:
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发表时间:
1978
影响因子:
11.1
通讯作者:
Y. Nakajima
Y. Nakajima
中科院分区:
综合性期刊1区
文献类型:
--
作者:
H. Peng;Y. Nakajima

文献摘要

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在非洲爪蟾胚胎肌细胞培养物中发现了成簇的膜颗粒聚集体。在有神经支配的培养物中,聚集物通常在神经附近发现。在颗粒密度和形态方面,它们类似于成年骨骼肌纤维的突触后颗粒聚集体,这表明它们可能与乙酰胆碱受体有关。在非神经支配的培养物中也发现了类似的颗粒聚集体。它们可能对应于乙酰胆碱受体的连接外簇或“热点”。"
Clusters of membrane particle aggregates were found in the cultures of Xenopus embryonic muscle cells. In innervated cultures, the aggregates were usually found in the vicinity of the nerve. In terms of particle density and morphology, they resembled the postsynaptic particle aggregates of adult skeletal muscle fibers, suggesting that they may be related to acetylcholine receptors. Similar particle aggregates were also found in noninnervated cultures. They may correspond to extrajunctional clusters of acetylcholine receptors or "hot spots."