SHOULD HIGHER VANCOMYCIN TROUGH LEVELS BE TARGETED FOR INVASIVE COMMUNITY-ACQUIRED METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS INFECTIONS IN CHILDREN?
SHOULD HIGHER VANCOMYCIN TROUGH LEVELS BE TARGETED FOR INVASIVE COMMUNITY-ACQUIRED METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS INFECTIONS IN CHILDREN?
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DOI：
10.1097/inf.0b013e3181c52a04
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发表时间：
2010-04-01
影响因子：
3.6
通讯作者：
Creech, C. Buddy
中科院分区：
文献类型：
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作者：
Jimenez-Truque, Natalia;Thomsen, Isaac;Creech, C. Buddy
Methicillin-resistant Staphylococcus aureus isolates with vancomycin minimal inhibitory concentrations (MICs) >= 1.5 mu g/mL have been associated with poorer clinical outcomes and treatment failures in adults. We evaluated vancomycin MICs in 71 invasive pediatric community-acquired MRSA isolates from 2004 to 2008, using the E-test micromethod and the E-test macro-method. The modal MIC by micromethod was 1.5 mu g/mL, and median vancomycin MICs did not increase over time.
