Dietary fatty acid profile affects endurance in rats
Dietary fatty acid profile affects endurance in rats
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DOI：
10.1007/s11745-006-0162-5
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发表时间：
1997-12-01
期刊：
影响因子：
1.9
通讯作者：
Hulbert, AJ
中科院分区：
文献类型：
--
作者：
Ayre, KJ;Hulbert, AJ
通常情况下，建议运动员增加碳水化合物的能量消耗，并沿着一般人群，减少饱和脂肪的消耗。现在人们认识到，脂肪对新陈代谢的影响是不一样的，我们认为，多不饱和脂肪成分的组成不应被忽视。本研究的目的是在高碳水化合物饮食中操纵膳食脂肪酸谱，以研究膳食多不饱和化合物对大鼠次极量耐力表现的影响。大鼠喂含22能量百分比（E%）脂肪的三种等能饮食之一，为期9周。饮食包括必需脂肪酸缺乏饮食（主要含有饱和脂肪酸）; n-6脂肪酸高的饮食，高n-6;和富含n-3脂肪酸的饮食，高n-3。喂食高n-3饮食的大鼠的次最大耐力比喂食高n-6饮食的大鼠低44%（P< 0.02）。然后，所有大鼠喂食标准的商业实验室饮食6周的恢复期，并重新评估其性能。尽管所有组的耐力均低于第9周，但高n-3组的耐力再次显著低于高n-6组的50%（P < 0.005）。虽然n-3脂肪被认为对心血管健康有益，但它们似乎会减少耐力时间，其副作用需要进一步研究。
Typically, athletes are advised to increase their consumption of carbohydrates for energy and, along with the general population, to reduce consumption of saturated fats. It is now recognized that fats are not identical in their influence on metabolism, and we argue that the composition of the polyunsaturated fat component should not be ignored. The aim of this study was to manipulate the dietary fatty acid profile in a high-carbohydrate diet in order to investigate the effect of dietary polyunsaturates on submaximal endurance performance in rats. Rats were fed one of three isoenergetic diets containing 22 energy percentage (E%) fat for 9 wk. The diets comprised an essential fatty acid-deficient diet (containing mainly saturated fatty acids); a diet high in n-6 fatty acids, High n-6; and a diet enriched with n-3 fatty acids, High n-3. Submaximal endurance in rats fed the High n-3 diet was 44% less than in rats fed the High n-6 diet (P< 0.02). All rats were then fed a standard commercial laboratory diet for a 6-wk recovery period, and their performances were reevaluated. Although endurance in all groups was lower than at 9 wk, it was again significantly 50% lower in the High n-3 group than the High n-6 group (P < 0.005). Although n-3 fats are considered beneficial for cardiovascular health, they appear to reduce endurance times, and their side effects need to be further investigated.