Patching retinal breaks with Seprafilm for treating retinal detachments in humans: 9 years of follow-up
Patching retinal breaks with Seprafilm for treating retinal detachments in humans: 9 years of follow-up
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DOI：
10.1038/eye.2016.329
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发表时间：
2017-05-01
期刊：
影响因子：
3.9
通讯作者：
Yamakawa, R.
中科院分区：
文献类型：
--
作者：
Haruta, M.;Arai, M.;Yamakawa, R.
目的描述4例视网膜脱离患者使用Seprafilm作为一种新的technique.Methods的长期手术结果Seprafilm覆盖视网膜裂孔在4只眼睛后，白内障手术，睫状体平坦部玻璃体切除术，液体-空气交换，激光光凝。既不使用长期存在的气体，也不使用硅油。没有指示患者保持一个特定的头部定位postoperation.Results成功的视网膜复位，实现了一个单一的手术在所有四只眼睛，没有发展增殖性玻璃体视网膜病变。术前和术后9年的平均最佳矫正视力分别为20/97和20/33。术后几天眼压升高，持续时间不超过2周。术后检测到鼻下或颞下象限的视野缺损。术前手术眼与对侧眼的视网膜电图a、b波振幅比值分别为0.68和0.64，术后分别为0.87和0.92。角膜内皮细胞密度术前平均为2365 cells/mm 2，术后平均为2592 cells/mm 2。结论Seprafilm覆盖视网膜裂孔可促进视网膜复位，无需气体填充和术后头部定位。术后9年的视力结局显示眼内应用Seprafilm没有明显的不良影响。
Purpose To describe the long-term surgical outcomes of four patients treated for retinal detachment using Seprafilm as a novel technique.Methods Retinal breaks in four eyes were covered with Seprafilm using a transvitreal approach after cataract surgery, pars plana vitrectomy, fluid-air exchange, and laser photocoagulation. Neither long-standing gas nor silicone oil was used. The patients were not instructed to maintain a specific head positioning postoperatively.Results Successful retinal reattachment was achieved with a single surgery in all four eyes, and none developed proliferative vitreoretinopathy. The mean best-corrected visual acuity preoperatively and 9 years postoperatively were 20/97 and 20/33, respectively. The intraocular pressure increased several days postoperatively that lasted no longer than 2 weeks. Visual field defects either in the inferonasal or inferotemporal quadrant were detected postoperatively. The mean electroretinogram a-and b-wave amplitude ratios of the operated eyes to the fellow eyes were 0.68 and 0.64 preoperatively and 0.87 and 0.92 postoperatively, respectively. The mean corneal endothelial cell density was 2365 cells/mm(2) preoperatively and 2592 cells/mm(2) postoperatively.Conclusion Covering retinal breaks with Seprafilm may promote retinal reattachment without gas tamponade and postoperative head positioning. The visual outcomes 9 years postoperatively showed no apparent adverse effects of intraocular application of Seprafilm.