PREDICTION OF APICAL THROMBUS FORMATION IN ACUTE MYOCARDIAL-INFARCTION BASED ON LEFT-VENTRICULAR SPATIAL FLOW PATTERN
PREDICTION OF APICAL THROMBUS FORMATION IN ACUTE MYOCARDIAL-INFARCTION BASED ON LEFT-VENTRICULAR SPATIAL FLOW PATTERN
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DOI：
10.1016/s0735-1097(10)80062-2
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发表时间：
1990-02-01
影响因子：
24
通讯作者：
DEKONING, H
中科院分区：
文献类型：
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作者：
DELEMARRE, BJ;VISSER, CA;DEKONING, H
对62例急性心肌梗死患者的左心室空间血流模式进行了血栓形成的预测。脉冲多普勒超声心动图显示：1)血液运动在二尖瓣和尖顶水平同时开始，2)沿侧壁和室间隔有不连续的多普勒信号。在发病后24小时内以及6周和12周后，按照这些标准评估流型。62例患者中有46例在首次检查时发现血流模式正常；在研究期间，这46名患者均未出现血栓。16例患者首次检查时出现异常血流模式；在6例患者的随访中，这种模式正常化，没有一例发生血栓。在其他10例患者中，异常血流模式持续存在，其中7例发生血栓。这些结果表明，急性心肌梗死时正常的左心室血流模式与随后的血栓形成无关。如果考虑抗凝，这一观察结果可能是重要的。
The predictive value of the left ventricular spatial flow pattern for thrombus formation was determined in 62 patients with acute myocardial infarction. A normal flow pattern by pulsed Doppler echocardiography was characterized by 1) simultaneous onset of blood motion at the mitral valve and apical level, and 2) a discontinuous Doppler signal along the lateral wall and interventricular septum. The flow pattern was assessed by these criteria, within 24 h after the onset of complaints and after 6 and 12 weeks. In 46 of the 62 patients, a normal flow pattern was found at the first examination; none of these 46 patients developed a thrombus during the study period. An abnormal flow pattern was seen at the first examination in 16 patients; this pattern normalized during follow-up in 6 patients, none of whom developed a thrombus. In the other 10 patients the abnormal flow pattern persisted, and 7 of these developed a thrombus. These findings suggest that a normal left ventricular flow pattern in the setting of acute myocardial infarction is not associated with subsequent thrombus formation. This observation may be of importance if anticoagulation is considered.