A multicentre study of 95 biopsy-proven cases of renal disease in primary Sjogren's syndrome
A multicentre study of 95 biopsy-proven cases of renal disease in primary Sjogren's syndrome
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DOI：
10.1093/rheumatology/kew376
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发表时间：
2017-03-01
期刊：
影响因子：
5.5
通讯作者：
Terrier, Benjamin
中科院分区：
文献类型：
--
作者：
Jasiek, Magali;Karras, Alexandre;Terrier, Benjamin
目标。肾脏受累是原发性SS （pSS）的罕见事件。我们的目的是描述pss相关肾病的临床生物学和组织病理学特征及其对治疗的反应。我们在法国进行了一项全国性的、回顾性的、多中心的研究，纳入了符合欧美共识组标准或扩大的欧美共识组标准的pSS患者，并活检证实肾脏受累。共纳入95例患者（中位年龄49岁）。估计肾小球滤过率（eGFR）为
Objective. Renal involvement is a rare event during primary SS (pSS). We aimed to describe the clinico-biological and histopathological characteristics of pSS-related nephropathy and its response to treatment.Methods. We conducted a French nationwide, retrospective, multicentre study including pSS patients fulfilling American-European Consensus Group criteria or enlarged American-European Consensus Group criteria, and with biopsy-proven renal involvement.Results. A total of 95 patients were included (median age 49 years). An estimated glomerular filtration rate (eGFR) of