TRP Channels in Female Reproductive Organs and Placenta
TRP Channels in Female Reproductive Organs and Placenta
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DOI：
10.1007/978-94-007-0265-3_47
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发表时间：
2011-01-01
期刊：
影响因子：
--
通讯作者：
Fecher-Trost, Claudia
中科院分区：
文献类型：
--
作者：
Doerr, Janka;Fecher-Trost, Claudia
TRP通道蛋白在女性生殖器官中广泛表达。根据在女性生殖器官和胎盘不同部位检测 TRP 转录本和蛋白质的研究，它们被认为参与卵母细胞或胚泡通过输卵管的运输、胚泡的植入、胎盘的发育以及跨越母胎屏障的运输过程。此外，分娩期间和乳腺中的子宫收缩性和生理过程似乎依赖于 TRP 通道表达。
TRP channel proteins are widely expressed in female reproductive organs. Based on studies detecting TRP transcripts and proteins in different parts of the female reproductive organs and placenta they are supposed to be involved in the transport of the oocyte or the blastocyte through the oviduct, implantation of the blastocyte, development of the placenta and transport processes across the feto-maternal barrier. Furthermore uterus contractility and physiological processes during labour and in mammary glands seem to be dependant on TRP channel expression.