SURVIVAL IN 1001 PATIENTS WITH CARCINOMA OF THE PANCREAS
SURVIVAL IN 1001 PATIENTS WITH CARCINOMA OF THE PANCREAS
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DOI：
10.1097/00000658-198709000-00015
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发表时间：
1987-09-01
影响因子：
9
通讯作者：
LOWENSTEIN, F
中科院分区：
文献类型：
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作者：
CONNOLLY, MM;DAWSON, PJ;LOWENSTEIN, F
1001例胰腺癌患者中，912例外分泌癌患者中有23例存活3年，46例壶腹癌患者中有10例存活3年，43例恶性胰岛细胞瘤患者中有21例存活3年。97例外分泌癌幸存者中，有9例行根治性手术，2例仅行姑息性切除，1例为偶发微灶性癌；在其余11例患者中，胰腺的组织学起源尚未确定。术前怀疑并经组织学证实的3年存活者包括6例导管腺癌、3例粘液囊腺癌、1例腺泡细胞癌和1例微腺癌。只有两个病人可以被认为治愈了。肿瘤大小和淋巴结状态与生存率无关。囊腺癌占病例的1%，但占3年幸存者的三分之一。组织学证实的胰腺癌的长期生存是一种罕见的事件，不能在个别病例中预测。
Among 1001 patients with carcinoma of the pancreas, 23 of 912 patients with exocrine carcinomas, 10 of 46 with ampullary carcinomas, and 21 of 43 with malignant islet cell tumors survived 3 years. Of the survivors with exocrine cancers, there were nine of 97 patients who had curative operation, two had had palliative resections only, and one was an incidental microfocal carcinoma; in the remaining 11 patients a histologic origin in the pancreas was not established. Preoperatively suspected and histologically proven 3-year survivors included six patients with ductal adenocarcinomas, three patients with mucinous cystadenocarcinomas, one patient with acinic cell carcinoma, and one patient with microadenocarcinoma. Only two patients can be considered cured. Tumor size and lymph node status did not correlate with survival. Cystadenocarcinomas comprised 1% of cases but one third of 3-year survivors. Long-term survival in histologically confirmed pancreatic carcinoma is a rare event that cannot be predicted in the individual case.