Iron complex-based fluorescent probes for intracellular hydrogen peroxide detection

Iron complex-based fluorescent probes for intracellular hydrogen peroxide detection
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DOI:
10.1039/c3cc44471f
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发表时间:
2013-01-01
影响因子:
4.9
通讯作者:
Kodera, Masahito
Kodera, Masahito
中科院分区:
化学2区
文献类型:
--
作者:
Hitomi, Yutaka;Takeyasu, Toshiyuki;Kodera, Masahito

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基于金属的H2O2的荧光探针,命名为MBFh2,即使在5 μ M H2O2的存在下,也能在秒的时间尺度内释放高度荧光的试卤灵。MBFh2的使用使得能够可视化的细胞内H2O2刺激后产生的表皮生长因子。
A metal-based fluorescent probe for H2O2, named MBFh2, releases a highly fluorescent resorufin in the seconds time scale even in the presence of 5 mu M H2O2. The use of MBFh2 enabled the visualization of intracellular H2O2 that was generated after stimulation of the epidermal growth factor.