EVALUATING THE PHYLOGENETIC UTILITY OF GENES - A SEARCH FOR GENES INFORMATIVE ABOUT DEEP DIVERGENCES AMONG VERTEBRATES
EVALUATING THE PHYLOGENETIC UTILITY OF GENES - A SEARCH FOR GENES INFORMATIVE ABOUT DEEP DIVERGENCES AMONG VERTEBRATES
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DOI：
10.2307/2413460
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发表时间：
1994-06-01
影响因子：
6.5
通讯作者：
GRAYBEAL, A
中科院分区：
文献类型：
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作者：
GRAYBEAL, A
在系统研究中广泛使用的基因已被证明对解决相对较浅（300 MYA）的分歧很有价值，但对中度深分歧有用的基因一直缺乏。计算机化的基因序列数据库正在迅速发展，并提供了丰富的基因资源，可能包含有关许多水平的分歧的系统发育信息。尽管事实上，所选择的基因必须适当地匹配的系统发育的分歧（S）的利益，很少有人注意到基因的可能的系统发育效用的估计和/或评估。生物体之间的基因序列通常是可用的系统发育关系和分歧时间的知识提供了一个强大的工具，估计这种效用。我进行了一项调查，目的是确定最有前途的基因，调查分歧范围从大约50至200 MYA的两栖动物分支。共鉴定出9个核蛋白基因。这些基因可能是有用的分类学家工作的类群具有相似的分歧时间，一般的方法可以作为一个例子，如何其他这样的调查可以进行。
Genes widely used in systematic studies have proven valuable for the resolution of relatively shallow (300 MYA) divergences, but genes useful for moderately deep divergences have been lacking. Computerized data bases of gene sequences are growing at a rapid pace and provide a rich resource of genes likely to contain phylogenetic information about many levels of divergence. Despite the fact that the chosen gene must be appropriately matched to the phylogenetic divergence(s) of interest, little attention has been given to the estimation and/or evaluation of the likely phylogenetic utility of genes. Knowledge of the phylogenetic relationships and divergence times among organisms for which gene sequences are commonly available provides a powerful tool for estimating this utility. I conducted a survey with the goal of identifying the most promising genes for investigating divergences ranging from approximately 50 to 200 MYA in an amphibian clade. Nine nuclear protein genes were identified. These genes may be useful to systematists working on taxa with similar divergence times, and the general approach may serve as an example of how other such surveys could be conducted.