Considerations for causality assessment of neurological and neuropsychiatric complications of SARS-CoV-2 vaccines: from cerebral venous sinus thrombosis to functional neurological disorder.
Considerations for causality assessment of neurological and neuropsychiatric complications of SARS-CoV-2 vaccines: from cerebral venous sinus thrombosis to functional neurological disorder.
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DOI：
10.1136/jnnp-2021-326924
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发表时间：
2021-11
期刊：
影响因子：
--
通讯作者：
Nicholson TR
中科院分区：
文献类型：
--
作者：
Butler M;Tamborska A;Wood GK;Ellul M;Thomas RH;Galea I;Pett S;Singh B;Solomon T;Pollak TA;Michael BD;Nicholson TR
科学界通过开发新型SARS-CoV-2疫苗迅速应对COVID-19大流行（表1）。截至2021年6月初，全球估计已接种20亿剂疫苗。1免疫接种后的神经系统不良事件（ARF），如脑静脉窦血栓形成和脱髓鞘事件，已被报道。在一些国家，这导致疫苗试验和推广方案暂时停止。由于缺乏明确证据表明疫苗和不良事件之间存在因果关系，或者AEFI本身很罕见，因此迄今为止已经重新启动了计划，尽管有时对建议进行了修改。2
The scientific community rapidly responded to the COVID-19 pandemic by developing novel SARS-CoV-2 vaccines (table 1). As of early June 2021, an estimated 2 billion doses have been administered worldwide. 1 Neurological adverse events following immunisation (AEFI), such as cerebral venous sinus thrombosis and demyelinating episodes, have been reported. In some countries, these have led to the temporary halting of both vaccine trials and roll-out programmes. In the absence of clear evidence of causal associations between the vaccine and adverse events, or the rarity of the AEFIs themselves, programmes have thus far been restarted, although sometimes with modifications to recommendations. 2
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DOI：
10.1056/nejmoa2104840
发表时间：
2021-06-03
期刊：
The New England journal of medicine
影响因子：
--
作者：
Greinacher A;Thiele T;Warkentin TE;Weisser K;Kyrle PA;Eichinger S
通讯作者：
Eichinger S
影响因子：
29
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DOI：
10.1056/nejmoa2035389
发表时间：
2021-02-04
期刊：
The New England journal of medicine
影响因子：
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DOI：
10.1016/s1473-3099(21)00065-7
发表时间：
2021-04
期刊：
The Lancet. Infectious diseases
影响因子：
--
作者：
Fairgrieve D;Holm S;Howells G;Kirchhelle C;Vanderslott S
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影响因子：
33.9
作者：
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通讯作者：
Shay, David K.