Hierarchical Assembly of Star Polymer Polymersomes into Responsive Multicompartmental Microcapsules
Hierarchical Assembly of Star Polymer Polymersomes into Responsive Multicompartmental Microcapsules
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DOI：
10.1021/acs.chemmater.5b04934
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发表时间：
2016-01
影响因子：
8.6
通讯作者：
Weinan Xu;A. Steinschulte;F. Plamper;V. Korolovych;V. Tsukruk
中科院分区：
文献类型：
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作者：
Weinan Xu;A. Steinschulte;F. Plamper;V. Korolovych;V. Tsukruk
我们报告了一种新的方法来实现可编程的封装和以下释放不同的化合物在一个顺序的方式从多室的微胶囊组装从预先形成的聚合物。通过阳离子杂臂星星聚合物（即聚（环氧乙烷）113-（季铵化的聚（2-（二甲基氨基）甲基丙烯酸乙酯）60）4）和线性阴离子聚合物（聚（苯乙烯磺酸盐）20）之间的静电相互作用形成聚合物囊泡或聚合物囊泡，然后用作主要组分以通过氢键逐层组装来制造具有单宁酸的微胶囊。单宁酸和聚合物囊泡之间的氢键对外部pH敏感，并且聚合物囊泡的结构强烈地依赖于周围介质的离子强度。这种组合促进了这些基于多室聚合物体的微胶囊的双重响应行为，可编程释放两种不同类型的封装分子（阴离子和阳离子）。
We report a novel approach to realizing programmable encapsulation and following release of different compounds in a sequential way from multicompartmental microcapsules assembled from preformed polymersomes. The polymersomes, or polymeric vesicles, are formed through electrostatic interactions between a cationic miktoarm star polymer, namely poly(ethylene oxide)113-(quaternized poly(2-(dimethylamino)ethyl methacrylate)60)4, and a linear anionic polyelectrolyte, (poly(styrenesulfonate)20), and then used as the main component to fabricate microcapsules with tannic acid via hydrogen-bonded layer-by-layer assembly. The hydrogen bonding between tannic acid and polymersomes is sensitive to external pH, and the structure of the polymersomes strongly depends on the ionic strength of the surrounding media. This combination facilitates dual-responsive behavior of these multicompartmental polymersome-based microcapsules with the programmable release of two different types of encapsulated molecules (anionic and cati...