Polypyrrole nanoprobes with low non-specific protein adsorption for intracellular mRNA detection and photothermal therapy
Polypyrrole nanoprobes with low non-specific protein adsorption for intracellular mRNA detection and photothermal therapy
复制标题
用于细胞内 mRNA 检测和光热治疗的低非特异性蛋白质吸附聚吡咯纳米探针
DOI:
10.1039/c5cc01129a
复制
发表时间:
2015-01-01
影响因子:
4.9
通讯作者:
Yang, Huang-Hao
中科院分区:
文献类型:
--
作者:
Ke, Kaimei;Lin, Lisen;Yang, Huang-Hao
In this work, we discovered that polypyrrole nanoparticles (PPy NPs) displayed a low non-specific protein adsorption. We herein present the first PPy NP-based biosensing platform for intracellular mRNA detection in living cells. We also demonstrate that PPy NPs exhibit high NIR absorbance and can be utilized for cancer photothermal therapy.