Respiratory failure due to muscle weakness in inflammatory myopathies:: maintenance therapy with home mechanical ventilation
Respiratory failure due to muscle weakness in inflammatory myopathies:: maintenance therapy with home mechanical ventilation
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DOI：
10.1093/rheumatology/39.8.914
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发表时间：
2000-08-01
期刊：
影响因子：
5.5
通讯作者：
Vilardell-Tarrés, M
中科院分区：
文献类型：
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作者：
Selva-O'Callaghan, A;Sanchez-Sitjes, L;Vilardell-Tarrés, M
多发性肌炎和皮肌炎是特发性炎性肌病。呼吸系统并发症是一个共同的特点，但呼吸功能不全是罕见的，在这些患者。我们在这里描述三名患者诊断为炎性肌病（多发性肌炎）与呼吸衰竭，由于肌肉无力谁没有反应的免疫抑制治疗。在家中采用鼻或气管间歇正压机械通气可改善慢性通气不足。这种治疗提高了炎症性肌病患者的生活质量，在某些情况下可以挽救生命。
Polymyositis and dermatomyositis are idiopathic inflammatory myopathies. Respiratory complications are a common feature, but ventilatory insufficiency is rare in these patients. We describe here three patients diagnosed with inflammatory myopathy (polymyositis) with respiratory failure due to muscle weakness who did not respond to immunosuppressive therapy. Mechanical ventilation at home with nasal or tracheal intermittent positive pressure resulted in improved chronic hypoventilation. This treatment improves the quality of life of patients with inflammatory myopathies and can be lifesaving in some cases.