SABmark - a benchmark for sequence alignment that covers the entire known fold space

SABmark - a benchmark for sequence alignment that covers the entire known fold space
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DOI:
10.1093/bioinformatics/bth493
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发表时间:
2005-04-01
期刊:
影响因子:
5.8
通讯作者:
Wyns, L
Wyns, L
中科院分区:
生物学3区
文献类型:
--
作者:
Van Walle, I;Lasters, I;Wyns, L

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摘要:序列比对基准(SABmark)提供了来自SCOP分类的多个比对问题的集合。这些集合,Twilight Zone和Superfamilies,都分别使用非常低到低和低到中等相似性的序列覆盖整个已知的折叠空间。此外,每个集合都有一个替代版本,其中不可解释但显然相似的序列被添加到每个问题中。
Summary: The Sequence Alignment Benchmark (SABmark) provides sets of multiple alignment problems derived from the SCOP classification. These sets, Twilight Zone and Superfamilies, both cover the entire known fold space using sequences with very low to low, and low to intermediate similarity, respectively. In addition, each set has an alternate version in which unalignable but apparently similar sequences are added to each problem.