The ICT filariasis test: A rapid-format antigen test for diagnosis of bancroftian filariasis
The ICT filariasis test: A rapid-format antigen test for diagnosis of bancroftian filariasis
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DOI：
10.1016/s0169-4758(97)01130-7
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发表时间：
1997-10-01
期刊：
影响因子：
--
通讯作者：
Weiss, N
中科院分区：
文献类型：
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作者：
Weil, GJ;Lammie, PJ;Weiss, N
抗原检测现在被认为是检测班氏吴策线虫感染的首选方法。与检测微丝蚴的测试不同，抗原测试可以用白天或晚上收集的血液进行。然而，现有的酶联免疫吸附试验（ELISA）检测丝虫抗原血症很难在现场进行，这限制了它们在流行国家的使用。在这篇文章中，加里韦尔，帕特里克Lammie和Niggi韦斯审查了他们的经验与一个新的快速格式丝虫抗原测试。他们发现ICT卡测试非常容易进行，并且在检测微丝蚴血症者血清中的丝虫抗原方面与ELISA相当。现在采用一种适合在实地使用的抗原测试是特别及时的，因为它可能有助于实施世界卫生组织提出的控制和消除淋巴丝虫病的新战略。
Antigen testing is now recognized as the method of choice for detection of Wuchereria bancrofti infections. Unlike tests that detect microfilariae, antigen tests can be performed with blood collected during the day or night. However, existing enzyme-linked immunosorbent assay (ELISA) tests for filarial antigenemia are difficult to perform in the field, and this has limited their use in endemic countries. In this article, Gary Weil, Patrick Lammie and Niggi Weiss review their experience with a new rapid-format filarial antigen test. They found that the ICT card test was very easy to perform and that it was comparable with ELISA for the detection of filarial antigen in sera from people with microfilaremia. The introduction now of an antigen test suitable for use in the field is especially timely, in that it may facilitate implementation of new strategies proposed by the World Health Organization for control and elimination of lymphatic filariasis.