Fatigue in systemic lupus erythematosus.
Fatigue in systemic lupus erythematosus.
复制标题
DOI：
10.2217/ijr.12.4
复制
发表时间：
2012-04-01
期刊：
影响因子：
--
通讯作者：
Ramsey-Goldman R
中科院分区：
文献类型：
--
作者：
Ahn GE;Ramsey-Goldman R
Systemic lupus erythematosus is a chronic inflammatory autoimmune disease often characterized by fatigue, with significant effects on physical functioning and wellbeing. The definition, prevalence and factors associated with fatigue, including physical activity, obesity, sleep, depression, anxiety, mood, cognitive dysfunction, vitamin D deficiency/insufficiency, pain, effects of medications and comorbidities, as well as potential therapeutic options of fatigue in the systemic lupus erythematosus population are reviewed. Due to variability in the reliability and validity of various fatigue measures used in clinical studies, clinical trial data have been challenging to interpret. Further investigation into the relationships between these risk factors and fatigue, and improved measures of fatigue, may lead to an improvement in the management of this chronic inflammatory disease.
