Asymptomatic Malaria Correlates with Anaemia in Pregnant Women at Ouagadougou, Burkina Faso
Asymptomatic Malaria Correlates with Anaemia in Pregnant Women at Ouagadougou, Burkina Faso
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DOI：
10.1155/2012/198317
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发表时间：
2012-01-01
影响因子：
--
通讯作者：
Simpore, Jacques
中科院分区：
文献类型：
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作者：
Douamba, Zoenabo;Bisseye, Cyrille;Simpore, Jacques
撒哈拉以南非洲每年约有3200万孕妇生活在恶性疟原虫高传播地区，导致疟疾。这项研究的目的是确定孕妇中无症状疟疾的流行率，并强调其对血液学标志物的影响。孕妇中恶性疟原虫无症状感染的患病率分别为30%和24%，快速检测试验（RDT）和显微镜。使用磺胺嘧啶-乙胺嘧啶间歇预防性治疗的孕妇中恶性疟原虫无症状疟疾的患病率降低，61%的孕妇贫血。与未感染的孕妇相比，感染恶性疟原虫的妇女贫血的发生率明显更高。大多数妇女的同型半胱氨酸水平正常，叶酸水平低。因此，应将疟疾的系统诊断作为产前保健的一部分介绍给孕妇。
Sub-Saharan Africa records each year about thirty-two million pregnant women living in areas of high transmission of Plasmodium falciparum causing malaria. The aim of this study was to carve out the prevalence of asymptomatic malaria among pregnant women and to emphasize its influence on haematological markers. The prevalence of Plasmodium falciparum asymptomatic infection among pregnant women was 30% and 24% with rapid detection test (RDT) and microscopy, respectively. The prevalence of P. falciparum asymptomatic malaria was reduced among pregnant women using sulfadoxine-pyrimethamine's intermittent preventive treatment and 61% of them were anaemic. Anaemia was significantly more common in women infected with P. falciparum compared with the uninfected pregnant women. Most of the women had normal levels of homocysteine and low levels of folate, respectively. Therefore, the systematic diagnosis of malaria should be introduced to pregnant women as a part of the antenatal care.