Protein folding: salty sea regulators of cystic fibrosis.

Protein folding: salty sea regulators of cystic fibrosis.
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蛋白质折叠:囊性纤维化的咸海调节剂。

DOI:
10.1038/nchembio.1144
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发表时间:
2013
影响因子:
14.8
通讯作者:
Balch,WilliamE
Balch,WilliamE
中科院分区:
生物学1区
文献类型:
--
作者:
Gupta,Vijay;Balch,WilliamE

文献摘要

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New, bioactive marine sponge compounds that function as inhibitors of the poly (ADP-ribose) polymerase family of proteins have now been identified to promote the correction of cystic fibrosis. Poly (ADP-ribose) polymerase inhibitors may be managers of proteostasis biology, consistent with their role (or roles) in remediation of inflammatory states.