Sesquiterpenoids and an ergosterol from cultures of the fungus Daedaleopsis tricolor

Sesquiterpenoids and an ergosterol from cultures of the fungus Daedaleopsis tricolor
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DOI:
10.1007/s13659-013-0065-0
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发表时间:
2013-11-25
影响因子:
4.7
通讯作者:
Liu JK
Liu JK
中科院分区:
化学4区
文献类型:
--
作者:
Zhao JY;Feng T;Li ZH;Dong ZJ;Zhang HB;Liu JK

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从三色担子菌中分离到4个新的双abolane倍半萜类化合物daedatrins a - d(1-4)、1个癸烷倍半萜类化合物12-羟基-α-二醇(5)和1个庚烷过甾烷衍生物daedatrins G(6)。它们的结构通过包括广泛的二维核磁共振技术和x射线晶体学在内的光谱方法得到了阐明。所有化合物对5种人类癌细胞系均无显著活性。本文的补充材料在10.1007/s13659-013-0065-0,授权用户可以访问。
Four new bisabolane sesquiterpenoids daedatrins A-D (1–4), a cadinane sesquiterpene 12-hydroxy-α-cadinol (5), and a heptanorergosterane derivative daedatrin G (6) were isolated from cultures of the basidiomycete Daedaleopsis tricolor. Their structures were elucidated by spectroscopic methods including extensive 2D NMR techniques and X-ray crystallography. All the compounds showed no significant activity against five human cancer cell lines. Supplementary material is available for this article at 10.1007/s13659-013-0065-0 and is accessible for authorized users.