Spatial and Frequency Specific Artifact Reduction in Optically Pumped Magnetometer Recordings.
Spatial and Frequency Specific Artifact Reduction in Optically Pumped Magnetometer Recordings.
复制标题
DOI：
10.31083/j.jin2105145
复制
发表时间：
2022-08-16
影响因子：
1.8
通讯作者：
Barnes-Davis, Maria E.
中科院分区：
文献类型：
--
作者：
Xiang, Jing;Tong, Han;Jiang, Yang;Barnes-Davis, Maria E.
关键词：
基于光泵磁强计(OPM)的脑磁图(MEG)为脑研究提供了新的机遇。然而，OPM录制与人工制品相关联。为了提高OPM记录的信噪比，我们提出了一种新的伪影抑制方法--频率特定信号空间分类(FSSSC)。FSSSC基于时频分析和信号空间分类(SSC)。SSC通过计算脑信号和伪影的正交性来完成。使用偶极子模型来确定该方法是否能够去除伪影并提高震源定位的精度。由于双侧听觉诱发磁场已被证明是测试新方法的良好基准，因此使用来自人类受试者的听觉诱发磁场(AEF)来评估伪影减少在脑功能研究中的有用性。来自空房间记录的OPM数据被用来估计磁性伪影。FSSSC的有效性在波形、频谱图和协方差域进行了评估。体模测试的脑磁图记录表明，FSSSC可以去除伪影，归一化波形，并显著提高源定位精度。来自人类受试者的脑磁图信号显示，FSSC可以揭示被伪影遮盖和扭曲的听觉诱发的磁反应。本研究表明，FSSSC在去除OPM记录中的伪影方面是有效的。这有助于分析波形、频谱图和协方差。FSSSC可以显著提高OPM记录的震源定位精度。被人工制品扭曲的大脑反应可以恢复。本研究的结果有力地支持了伪影的减少是非常重要的，以使OPMS成为传统脑磁图的可行替代品。
Magnetoencephalography (MEG) based on optically pumped magnetometers (OPMs) opens up new opportunities for brain research. However, OPM recordings are associated with artifacts. We describe a new artifact reduction method, frequency specific signal space classification (FSSSC), to improve the signal-to-noise ratio of OPM recordings. FSSSC was based on time-frequency analysis and signal space classification (SSC). SSC was accomplished by computing the orthogonality of the brain signal and artifact. A dipole phantom was used to determine if the method could remove artifacts and improve accuracy of source localization. Auditory evoked magnetic fields (AEFs) from human subjects were used to assess the usefulness of artifact reduction in the study of brain function because bilateral AEFs have proven a good benchmark for testing new methods. OPM data from empty room recordings were used to estimate magnetic artifacts. The effectiveness of FSSSC was assessed in waveforms, spectrograms, and covariance domains. MEG recordings from phantom tests show that FSSSC can remove artifacts, normalize waveforms, and significantly improve source localization accuracy. MEG signals from human subjects show that FSSC can reveal auditory evoked magnetic responses overshadowed and distorted by artifacts. The present study demonstrates FSSSC is effective at removing artifacts in OPM recordings. This can facilitate the analyses of waveforms, spectrograms, and covariance. The accuracy of source localization of OPM recordings can be significantly improved by FSSSC. Brain responses distorted by artifacts can be restored. The results of the present study strongly support that artifact reduction is very important in order for OPMs to become a viable alternative to conventional MEG.
登录
查看更多内容
影响因子：
3.7
作者：
Marhl U;Jodko-Władzińska A;Brühl R;Sander T;Jazbinšek V
通讯作者：
Jazbinšek V
影响因子：
8.6
作者：
Shah, V.;Vasilakis, G.;Romalis, M. V.
通讯作者：
Romalis, M. V.
影响因子：
3
作者：
Tal, I.;Abeles, M.
通讯作者：
Abeles, M.
影响因子：
2.7
作者：
Taulu, S;Kajola, M;Simola, J
通讯作者：
Simola, J
影响因子：
3.5
作者：
Shah VK;Wakai RT
通讯作者：
Wakai RT