Increased Frequency of Th17 Cells in Children With Mycoplasma pneumoniae Pneumonia
Increased Frequency of Th17 Cells in Children With Mycoplasma pneumoniae Pneumonia
复制标题
肺炎支原体肺炎儿童中 Th17 细胞频率增加
DOI：
10.1002/jcla.22005
复制
发表时间：
2016-11-01
影响因子：
2.7
通讯作者：
Su, Chuan
中科院分区：
文献类型：
--
作者：
Wang, Xiaowei;Chen, Xiaojun;Su, Chuan
肺炎支原体（M.肺炎支原体（MP）是全球公认的人类（尤其是儿童）原发性非典型肺炎的重要病因。过度的宿主免疫反应被认为是M.肺炎感染。虽然Th17细胞已被鉴定为清除病原体和诱导由过度免疫应答引起的自身免疫的关键调节剂，但对Th17细胞在M患者中的作用知之甚少。肺炎感染。
Mycoplasma pneumoniae (M. pneumoniae, MP) is recognized globally as a significant cause of primary atypical pneumonia in humans, particularly in children. Overzealous host immune responses are viewed as key mediators of the pathogenesis of M. pneumoniae infection. Although Th17 cells have been identified as key modulators in the clearance of pathogens and induction of autoimmunity caused by excessive immune responses, little is known about the role of Th17 cells in patients with M. pneumoniae infection.