Brachial and carotid hemodynamic response to hot water immersion in men and women.
Brachial and carotid hemodynamic response to hot water immersion in men and women.
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男性和女性对热水浸泡的肱动脉和颈动脉血流动力学反应。
DOI：
10.1152/ajpregu.00110.2021
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
Minson,ChristopherT
中科院分区：
文献类型：
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作者：
Larson,EmilyA;Ely,BrettR;Brunt,ViennaE;Francisco,MichaelA;Harris,SarianneM;Halliwill,JohnR;Minson,ChristopherT
这项研究试图比较健康的年轻男性和女性对热水浸泡(HWI)时的臂部和颈动脉血流动力学反应。10名女性(W)和11名男性(M)(24 ± 4岁)完成了60分钟的HWI训练，将其浸入40°C的水中至胸骨水平。分别在基础状态(坐位休息)和HWI期间每隔15分钟测量一次肱动脉和颈动脉血流动力学(多普勒超声)。在高强度加权时，肱动脉内的总切变率女性[+479(+364，+594)S−1]明显高于男性[+292(+222，+361)S−1](P=0.005)。由于剪切率与血管内径成反比，与血流速度成正比，因此女性对高强度扫描的臂部剪切反应的性别差异是由于女性在基线(P<；0.0001)和整个高强度扫描(性别的主效应，P<；与男性[+35(+27，+43)cm/S]相比，HW I患者的臂部血流速度增加幅度更大(P=0.047)，男女之间的臂部血流速度也有相似的增加[M：+369(+287，+451)毫升/分，W：+364(+243万，+486)毫升/分，P=0.943]。相比之下，在基线或整个HWI时，颈动脉总剪切率、血流、速度或直径在性别之间没有差异。这些数据表明，在对单次高强度磁共振的血流动力学反应中，存在动脉特异性性别差异。
This study sought to compare the brachial and carotid hemodynamic response to hot water immersion (HWI) between healthy young men and women. Ten women (W) and 11 men (M) (24 ± 4 yr) completed a 60-min HWI session immersed to the level of the sternum in 40°C water. Brachial and carotid artery hemodynamics (Doppler ultrasound) were measured at baseline (seated rest) and every 15 min throughout HWI. Within the brachial artery, total shear rate was elevated to a greater extent in women [+479 (+364, +594) s−1] than in men [+292 (+222, +361) s−1] during HWI (P= 0.005). As shear rate is inversely proportional to blood vessel diameter and directly proportional to blood flow velocity, the sex difference in brachial shear response to HWI was the result of a smaller brachial diameter among women at baseline (P< 0.0001) and throughout HWI (main effect of sex,P< 0.0001) and a greater increase in brachial velocity seen in women [+48 (+36, +61) cm/s] compared with men [+35 (+27, +43) cm/s] with HWI (P= 0.047) which allowed for a similar increase in brachial blood flow between sexes [M: +369 (+287, +451) mL/min, W: +364 (+243, +486) mL/min,P= 0.943]. In contrast, no differences were seen between sexes in carotid total shear rate, flow, velocity, or diameter at baseline or throughout HWI. These data indicate the presence of an artery-specific sex difference in the hemodynamic response to a single bout of HWI.