Changing the paradigm from 'race' to human genome variation
Changing the paradigm from 'race' to human genome variation
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DOI：
10.1038/ng1454
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发表时间：
2004-11-01
期刊：
影响因子：
30.8
通讯作者：
Dunston, GM
中科院分区：
文献类型：
--
作者：
Royal, CDM;Dunston, GM
来自人类基因组计划和人类基因组变异研究的知识越来越多地挑战“种族”一词对人类群体的适用性，对生物医学和科学文献中关于“种族”的推断的有效性提出了质疑。尽管当代科学中存在着公认的矛盾，但基于人群的遗传变异仍被不断地用来解释“种族”和“民族”群体之间的健康差异。在这篇评论中，我们重申，解决生物学与“种族”和遗传学之间明显的矛盾需要“跳出框框”的思考。
Knowledge from the Human Genome Project and research on human genome variation increasingly challenges the applicability of the term 'race' to human population groups, raising questions about the validity of inferences made about 'race' in the biomedical and scientific literature. Despite the acknowledged contradictions in contemporary science, population-based genetic variation is continually used to explain differences in health between 'racial' and 'ethnic' groups. In this commentary we posit that resolution of apparent paradoxes in relating biology to 'race' and genetics requires thinking 'outside of the box'.