Maternal lipid intake during pregnancy and lactation alters milk composition and production and litter growth in rats
Maternal lipid intake during pregnancy and lactation alters milk composition and production and litter growth in rats
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DOI：
10.1093/jn/127.3.458
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发表时间：
1997-03-01
影响因子：
4.2
通讯作者：
Villalpando, S
中科院分区：
文献类型：
--
作者：
DelPrado, M;Delgado, G;Villalpando, S
研究了孕期和哺乳期饲喂等能量密度纯净日粮(含脂肪2.5g/100g和20g/100g)大鼠日粮脂肪含量与乳成分、产奶量和窝产仔数的关系。在另一项实验中，另一组大鼠(HL-EP组)喂食高脂(HL)饲料，但在能量基础上与低脂(LL)饲料组配对喂养。记录采食量、母猪体重和窝重。在哺乳期第14天给大鼠挤奶。测定乳脂、乳糖和蛋白质浓度及产奶量。饲喂HL饲料的哺乳期大鼠的能量摄入量(P<；0.01)和产奶量(P<；0.05)显著高于饲喂LL饲料的大鼠。HL组乳脂浓度、日产奶量和乳脂量显著高于HL组。HL-EP组乳脂、蛋白质和乳糖浓度显著高于LL组(P<；0.05)，日产脂量和能量输出量也明显高于LL组(P=0.08)。各组仔猪初生重相似，但从第6天开始，HL组和HL-EP组的仔猪体重显著高于LL组(P<；0.05)。这项研究表明，饮食脂肪调控改变了哺乳期大鼠的乳脂浓度以及脂肪、蛋白质和乳糖的日产量，进而影响了窝仔的生长。
The relationship between dietary fat content and milk composition, production and litter growth was studied in rats fed during pregnancy and lactation purified diets of equal energy density containing 2.5 or 20 g fat/100 g diet. A subsample of rats (HL-EP group) fed the high lipid (HL) diet but pair-fed on an energy basis with the low lipid (LL) diet group was also studied in a separate experiment. Food intake, dam body weight and litter weight were recorded dairy. Rats were milked on d 14 of lactation. Milk lipid, lactose and protein concentration and milk production were measured. Lactating rats fed the HL diet had significantly higher energy intakes (P < 0.01) and milk production (P < 0.05) than rats fed the LL diet. Milk lipid concentration and daily milk volume and lipid production were significantly higher in the HL group. The HL-EP dams had significantly higher milk lipid, protein and lactose concentrations (P < 0.05) and tended to have higher daily lipid and energy outputs (P = 0.08) than LL rats. Birth weights of pups were similar among groups, but from d 6 on, the pups from the HL and HL-EP groups were significantly heavier (P < 0.05) than pups from the LL group. This investigation presents evidence that the milk fat concentration and the daily output of fat, protein and lactose of lactating rats are altered by dietary fat manipulations, which in turn affect growth of the litter.