Multiple, independent, identical IS6110 insertions in Mycobacterium tuberculosis PPE genes
Multiple, independent, identical IS6110 insertions in Mycobacterium tuberculosis PPE genes
复制标题
DOI:
10.1016/j.tube.2009.08.001
复制
发表时间:
2009-11-01
期刊:
影响因子:
3.2
通讯作者:
Gey van Pittius, Nicolaas C.
中科院分区:
文献类型:
--
作者:
McEvoy, Christopher R. E.;Warren, Robin M.;Gey van Pittius, Nicolaas C.
IS6110 is a transposable element found in Mycobacterium tuberculosis complex members. Regions of preferential IS6110 integration occur within the M. tuberculosis genome but the element has not previously been shown to exhibit any sequence-specific integration preferences. Here we provide evidence for multiple independent IS6110 insertions into identical, or near-identical, positions within the highly homologous 50 region of 3 PPE genes. (C) 2009 Elsevier Ltd. All rights reserved.