The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative Diseases Working Group.
The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative Diseases Working Group.
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DOI：
10.1186/s13195-017-0254-x
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发表时间：
2017-04-17
期刊：
影响因子：
--
通讯作者：
Cappa SF
中科院分区：
文献类型：
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作者：
Costa A;Bak T;Caffarra P;Caltagirone C;Ceccaldi M;Collette F;Crutch S;Della Sala S;Démonet JF;Dubois B;Duzel E;Nestor P;Papageorgiou SG;Salmon E;Sikkes S;Tiraboschi P;van der Flier WM;Visser PJ;Cappa SF
认知、行为和功能评估在神经退行性痴呆（NDD）的纵向研究中至关重要。中心问题，如研究人群（无症状，风险，或患有痴呆症的个人）的定义，变化/下降的检测和相关结果的评估取决于认知，行为和功能状态的定量测量。目前，我们远没有可靠的协议和工具来评估欧洲的痴呆症。主要问题是不同欧洲国家使用的工具的异质性，缺乏标准化的管理和评分方法跨中心，以及有限的信息，目前广泛使用的许多测试的心理测量特性。这种情况使得很难比较不同中心开展的研究的结果，从而阻碍了研究进展，特别是对“大数据”共同数据集的贡献。我们在这里提出的结果，由神经退行性疾病联合计划（JPND）和意大利卫生部资助的项目。该项目旨在为评估工具的协调提供一个共识框架，以应用于影响整个欧洲认知的神经退行性疾病的研究。一个欧洲专家小组审查了目前的神经心理学评估方法，确定了悬而未决的问题，并提出了协调欧洲神经退行性痴呆神经心理学评估的建议。就制定神经心理学评估程序和工具时应遵循的一般性建议达成了共识，目的是协调工具和程序，以获得关于认知行为检查的更可靠数据。这项研究的结果应被视为第一步，以加强欧洲国家对NDD评估的共同观点和实践。
Cognitive, behavioural, and functional assessment is crucial in longitudinal studies of neurodegenerative dementias (NDD). Central issues, such as the definition of the study population (asymptomatic, at risk, or individuals with dementia), the detection of change/decline, and the assessment of relevant outcomes depend on quantitative measures of cognitive, behavioural, and functional status. Currently, we are far from having available reliable protocols and tools for the assessment of dementias in Europe. The main problems are the heterogeneity of the tools used across different European countries, the lack of standardisation of administration and scoring methods across centres, and the limited information available about the psychometric properties of many tests currently in widespread use. This situation makes it hard to compare results across studies carried out in different centres, thus hampering research progress, in particular towards the contribution to a “big data” common data set. We present here the results of a project funded by the Joint Program for Neurodegenerative Diseases (JPND) and by the Italian Ministry of Health. The project aimed at providing a consensus framework for the harmonisation of assessment tools to be applied to research in neurodegenerative disorders affecting cognition across Europe. A panel of European experts reviewed the current methods of neuropsychological assessment, identified pending issues, and made recommendations for the harmonisation of neuropsychological assessment of neurodegenerative dementias in Europe. A consensus was achieved on the general recommendations to be followed in developing procedures and tools for neuropsychological assessment, with the aim of harmonising tools and procedures to achieve more reliable data on the cognitive-behavioural examination. The results of this study should be considered as a first step to enhancing a common view and practise on NDD assessment across European countries.