Co-infection of Epstein-Barr virus and human papillomavirus in human tumorigenesis.
Co-infection of Epstein-Barr virus and human papillomavirus in human tumorigenesis.
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EB病毒和人乳头瘤病毒的共同感染在人类肿瘤发生中的作用
DOI：
10.1186/s40880-016-0079-1
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发表时间：
2016-01-22
影响因子：
--
通讯作者：
Cao Y
中科院分区：
文献类型：
--
作者：
Shi Y;Peng SL;Yang LF;Chen X;Tao YG;Cao Y
病毒感染导致全球约12%的癌症，其中绝大多数发生在发展中国家和地区。两种DNA病毒，EB病毒（EBV）和人乳头瘤病毒（HPV），与所有病毒相关癌症的38%相关。一个病人感染这两种不同类型病毒的可能性正在增加。在此，我们总结了人类恶性肿瘤中EBV和HPV的共感染，并讨论了肿瘤发生过程中EBV和HPV共感染的可能机制。
Viral infections contribute to approximately 12% of cancers worldwide, with the vast majority occurring in developing countries and areas. Two DNA viruses, Epstein-Barr virus (EBV) and human papillomavirus (HPV), are associated with 38% of all virus-associated cancers. The probability of one patient infected with these two distinct types of viruses is increasing. Here, we summarize the co-infection of EBV and HPV in human malignancies and address the possible mechanisms for the co-infection of EBV and HPV during tumorigenesis.