Long-Term Outcome of Kidney Transplantation in Recipients with Focal Segmental Glomerulosclerosis
Long-Term Outcome of Kidney Transplantation in Recipients with Focal Segmental Glomerulosclerosis
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DOI：
10.2215/cjn.03060316
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发表时间：
2016-11-01
影响因子：
9.8
通讯作者：
McTaggart, Steven J.
中科院分区：
文献类型：
--
作者：
Francis, Anna;Trnka, Peter;McTaggart, Steven J.
背景和目的FSGS可在肾移植后复发，并与移植物预后不良相关。我们的目的是评估移植后FSGS复发的发生率，并确定移植物来源对活检证实的FSGS患者的复发和移植物存活的影响。设计、设置、参与者和测量使用澳大利亚和新西兰透析和移植登记处，我们评估了FSGS的发生率，供体类型对FSGS复发风险的影响，结果1992年至2011年，在666例成人和70例儿童患者中进行了736例首次肾移植，
Background and objectives FSGS can recur after kidney transplantation and is associated with poor graft outcomes. We aimed to assess the incidence of FSGS recurrence post-transplant and determine the effect of graft source on recurrence and graft survival in patients with biopsy-proven FSGS.Design, setting, participants, & measurements Using the Australian and New Zealand Dialysis and Transplant Registry, we assessed incidence of FSGS, the influence of donor type on the risk of FSGS recurrence, and graft loss in recipients with ESRD caused by primary FSGS using Kaplan-Meier and logistic regression analyses.Results Between 1992 and 2011, 736 first kidney transplants were performed in 666 adults and 70 children (