Identity crisis: it's not just Foxp3 anymore.
Identity crisis: it's not just Foxp3 anymore.
复制标题
身份危机：不再只是 Foxp3。
DOI：
10.1016/j.immuni.2012.10.012
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发表时间：
2012
期刊：
影响因子：
32.4
通讯作者：
Vignali,DarioAA
中科院分区：
文献类型：
--
作者：
Delgoffe,GregM;Bettini,MatthewL;Vignali,DarioAA
制造调节性 T (Treg) 细胞需要什么？在本期《免疫》中，Ohkura 等人。结果表明，Treg 细胞特异性 CpG 低甲基化和 Foxp3 表达是 Treg 细胞发育、稳定性和完全抑制活性所需的独立事件。
What does it take to make a regulatory T (Treg) cell? In this issue ofImmunity, Ohkura et al. show that Treg-cell-specific CpG hypomethylation and Foxp3 expression are independent events required for Treg cell development, stability, and full suppressive activity.