Hepatitis C virus and intracellular antiviral response.
Hepatitis C virus and intracellular antiviral response.
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丙型肝炎病毒与细胞内抗病毒反应。
DOI：
10.1016/j.coviro.2021.12.010
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发表时间：
2022-03
影响因子：
5.9
通讯作者：
Ou JJ
中科院分区：
文献类型：
--
作者：
Lee J;Ou JJ
To establish successful infection in cells, it is essential for hepatitis C virus (HCV) to overcome intracellular antiviral responses. The host cell mechanism that fights against the virus culminates in the production of interferons (IFNs), IFN-stimulated genes (ISGs) and pro-inflammatory cytokines as well as the induction of autophagy and apoptosis. HCV has developed multiple means to disrupt the host signaling pathways that lead to these antiviral responses. HCV impedes signaling pathways initiated by pattern-recognition receptors (PRRs), usurps and uses the antiviral autophagic response to enhance its replication, alters mitochondrial dynamics and metabolism to prevent cell death and attenuate IFN response, and dysregulates inflammasomal response to cause IFN resistance and immune tolerance. These effects of HCV allow HCV to successful replicate and persist in its host cells.
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影响因子：
13.5
作者：
Fletcher, Nicola F.;Sutaria, Rupesh;Jo, Juandy;Barnes, Amy;Blahova, Miroslava;Meredith, Luke W.;Cosset, Francois-Loic;Curbishley, Stuart M.;Adams, David H.;Bertoletti, Antonio;McKeating, Jane A.
通讯作者：
McKeating, Jane A.
影响因子：
6
作者：
Chandra, Partha K.;Bao, Lili;Dash, Srikanta
通讯作者：
Dash, Srikanta
影响因子：
5.4
作者：
Daussy CF;Monard SC;Guy C;Muñoz-González S;Chazal M;Anthonsen MW;Jouvenet N;Henry T;Dreux M;Meurs EF;Hansen MD
通讯作者：
Hansen MD
DOI：
10.1073/pnas.1321114111
发表时间：
2014-04-29
影响因子：
11.1
作者：
Kim, Seong-Jun;Syed, Gulam H.;Siddiqui, Aleem
通讯作者：
Siddiqui, Aleem
影响因子：
25.7
作者：
Abid, K;Pazienza, V;Negro, F
通讯作者：
Negro, F