Disseminated lupus vulgaris.
Disseminated lupus vulgaris.
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播散性寻常狼疮。
DOI：
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发表时间：
2003
期刊：
影响因子：
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通讯作者：
G. Girolomoni
中科院分区：
文献类型：
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作者：
P. Gisondi;Marie Perez;E. Gubinelli;B. Cocuroccia;M. Fazio;G. Girolomoni
寻常狼疮是最常见的皮肤结核病，通常表现为面部的孤立性病变。我们报告了两名在不同皮肤区域出现多处病变的患者。第一个病人表现为右脚弥漫性受累，右腿、背部和面部出现红棕色斑块。病变扩散后，长期应用局部皮质类固醇。第二名患者在颈背和枕骨区域显示出大斑块，导致瘢痕性脱发，并且在右侧腹股沟和大腿区域显示出斑块。Ziehl-Neelsen染色均为阴性，但诊断得到组织学和聚合酶链反应分析的支持。无内脏受累。抗结核药物综合化疗起效快。
Lupus vulgaris is the most common form of cutaneous tuberculosis, and usually presents as a solitary lesion on the face. We report two patients with multiple lesions on different skin areas. The first patient presented a diffuse involvement of the right foot, and reddish-brown plaques on the right leg, the back and the face. Spreading of the lesions followed a prolonged application of topical corticosteroids. The second patient showed a large plaque on the nape and occipital area resulting in scarring alopecia, and plaques on the right inguinal and thigh regions. Ziehl-Neelsen staining was negative in both cases, but diagnosis was supported by histology and polymerase chain reaction analysis. No visceral involvement was present. Antituberculosis polychemotherapy was rapidly effective.