An active chromatin structure acquired by translocated c-myc genes.

An active chromatin structure acquired by translocated c-myc genes.
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通过易位 c-myc 基因获得的活性染色质结构。

DOI:
10.1128/mcb.6.4.1357-1361.1986
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发表时间:
1986
影响因子:
5.3
通讯作者:
Calame,K
Calame,K
中科院分区:
生物学2区
文献类型:
--
作者:
Kakkis,E;Prehn,J;Calame,K

文献摘要

相似文献

我们使用一般敏感性DNase I消化分析染色质结构的c-mycgenes在7个小鼠浆细胞瘤。在每种情况下,与Cα并列的c-mycor的3′部分显示出比未易位的c-mycor更敏感的染色质结构,在一个分析的情况下,与Cα并列的c-mycor的3 ′部分显示出比未易位的c-mycor更敏感的染色质结构。我们的数据表明Cα基因片段附近存在调节序列。
We used general sensitivity to DNase I digestion to analyze the chromatin structure of c-mycgenes in seven murine plasmacytomas. In every case, the 3′ portion of c-mycjuxtaposed with Cα displayed a much more DNase I-sensitive chromatin structure than untranslocated c-mycor, in one case analyzed, the reciprocally translocated 5′ portion. Our data suggest the presence of regulatory sequences near the Cα gene segment.