Spectrum of CD30+ lymphoid proliferations in the eyelid lymphomatoid papulosis, cutaneous anaplastic large cell lymphoma, and anaplastic large cell lymphoma.
Spectrum of CD30+ lymphoid proliferations in the eyelid lymphomatoid papulosis, cutaneous anaplastic large cell lymphoma, and anaplastic large cell lymphoma.
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眼睑淋巴瘤样丘疹病、皮肤间变性大细胞淋巴瘤和间变性大细胞淋巴瘤中 CD30 淋巴增殖的谱。
DOI：
10.1016/j.ophtha.2009.07.013
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发表时间：
2010
期刊：
影响因子：
13.7
通讯作者：
Grossniklaus,HansE
中科院分区：
文献类型：
--
作者：
Sanka,RKrishna;EagleJr,RalphC;Wojno,TedH;Neufeld,KennethR;Grossniklaus,HansE
目的报告3例眼睑CD30+淋巴组织增生性病变的临床病理特征。设计回顾病例系列。眼睑皮肤CD30+淋巴组织增生性病变。结果1例患者包括1例81岁男性、1例18岁男性和1例42岁女性眼睑及邻近软组织CD30+淋巴组织增生。第一例患者有一个孤立的陨石状眼睑病变，被归类为淋巴瘤样丘疹(LYP)。第二例患者有一个孤立的眼睑多结节病变，被归类为皮肤间变性大细胞淋巴瘤。第三例患者表现为眼皮浮肿和下层肿块，并被发现为广泛播散性间变性大细胞淋巴瘤(ALCL)。诊断取决于临床表现。结论CD30+淋巴组织增殖代表了一系列的疾病，从惰性的LYP，到中度侵袭性的CALCL，再到高度侵袭性的ALCL。对CD30+淋巴组织增生症的病理结果的解释部分是基于临床表现。财务披露(S)：作者对本文讨论的任何材料都没有专有或商业利益。
PURPOSETo report the clinicopathologic features of 3 patients with CD30+lymphoid proliferations of the eyelid.DESIGNRetrospective case series.PARTICIPANTSPatients with cutaneous CD30+lymphoproliferative lesions of the eyelid.METHODSThree patients with CD30+non-mycosis fungoides T-cell lymphoid infiltrates of the eyelid were identified. The histories, clinical findings, pathologic features including immunohistochemical staining, treatments, and outcomes were reviewed and compared.MAIN OUTCOME MEASURESPathologic findings including immunohistochemical analysis.RESULTSThe patients included an 81-year-old man, an 18-year-old man, and a 42-year-old woman with CD30+lymphoid proliferations of the eyelid and adjacent soft tissue. The first patient had an isolated crateriform eyelid lesion that was classified as lymphomatoid papulosis (LyP). The second patient had an isolated multinodular lesion of the eyelid that was classified as cutaneous anaplastic large cell lymphoma (cALCL). The third patient presented with eyelid edema with an underlying mass and was found to have widely disseminated anaplastic large cell lymphoma (ALCL). Diagnoses were dependent on clinical findings.CONCLUSIONSThe CD30+lymphoid proliferations represent a spectrum of conditions ranging from indolent LyP, to moderately aggressive cALCL, to highly aggressive ALCL. Interpretation of the pathologic findings in CD30+lymphoid proliferations is based in part on clinical findings. FINANCIAL DISCLOSURE(S): The authors have no proprietary or commercial interest in any material discussed in this article.
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影响因子：
1.7
作者：
Kyoung‐Ae Jang;Jung‐Chul Choi;Jee
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DOI：
--
发表时间：
1998
期刊：
American journal of ophthalmology-glaucoma
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DOI：
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期刊：
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影响因子：
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作者：
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影响因子：
20.3
作者：
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影响因子：
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作者：
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