Dissociating neural mechanisms of temporal sequencing and processing phonemes
Dissociating neural mechanisms of temporal sequencing and processing phonemes
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DOI：
10.1016/s0896-6273(03)00285-x
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发表时间：
2003-06-05
期刊：
影响因子：
16.2
通讯作者：
Bookheimer, SY
中科院分区：
文献类型：
--
作者：
Gelfand, JR;Bookheimer, SY
使用功能磁共振成像，我们试图确定是否后，上级部分布罗卡区执行操作的音素段具体或执行过程一般排序离散单位。12名健康志愿者进行了两个序列操作任务和一个匹配任务，使用音节串和哼唱音符。布罗卡区的后部专门响应序列操作任务，独立的刺激是否由音素或哼音符。相比之下，左缘上回是更具体的排序音素段。这些结果表明一个典型的左半球语言区域的功能分离，包括“语音回路”，左后额下回不响应语言的声音结构，而是顺序操作，可能是形成单词的能力的基础分离的元素。
Using fMRI, we sought to determine whether the posterior, superior portion of Broca's area performs operations on phoneme segments specifically or implements processes general to sequencing discrete units. Twelve healthy volunteers performed two sequence manipulation tasks and one matching task, using strings of syllables and hummed notes. The posterior portion of Broca's area responded specifically to the sequence manipulation tasks, independent of whether the stimuli were composed of phonemes or hummed notes. In contrast, the left supramarginal gyrus was somewhat more specific to sequencing phoneme segments. These results suggest a functional dissociation of the canonical left hemisphere language regions encompassing the "phonological loop," with the left posterior inferior frontal gyrus responding not to the sound structure of language but rather to sequential operations that may underlie the ability to form words out of dissociable elements.