A new meroterpenoid from endophytic fungus Talaromyces amestolkiae CS-O-1
A new meroterpenoid from endophytic fungus Talaromyces amestolkiae CS-O-1
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来自内生真菌Talaromyces amestolkiae CS-O-1的新类萜
DOI：
10.1016/j.bse.2020.104186
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发表时间：
2020-12-01
影响因子：
1.6
通讯作者：
Liu, Tao
中科院分区：
文献类型：
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作者：
Fu, Yunmei;Li, Chunhe;Liu, Tao
从雷公雷公藤中分离得到的一种叫Talaromyces amestolkiae CS-O-1的化合物。f.根据its和18S rDNA基因测序鉴定。从Talaromyces amestolkiae CS-O-1中分离得到一个新的二萜类化合物chrodrimanin T(1)和六个已知化合物烟酰胺(2)、penipyri酮D(3)、penipyri酮A(4)、3-苄基-8,8 -二羟基-2-甲基-六氢吡咯[1,2- A]吡嗪-1,4-二酮(5)、邻苯二甲酸丁异丁酯(6)和aspergillumarin A(7)。通过HRMS、1D和2D-NMR分析以及与文献数据的比较，确定了这些化合物的结构和相对构型。其中化合物2 ~ 6为首次从Talaromyces属中分离得到。本文描述了这些化合物的化学分类意义。
Talaromyces amestolkiae CS-O-1, isolated from Tripterygium Wilfordii Hook. f., was identified based on its ITS and 18S rDNA gene sequencing. A new meroterpenoid, chrodrimanin T (1), along with six known compounds, nicotinamide (2), penipyridone D (3), penipyridone A (4), 3-benzylidene-8,8a-dihydroxy-2-methyl-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione (5), butyl-isobutyl-phthalate (6), and aspergillumarin A (7), were isolated from Talaromyces amestolkiae CS-O-1. The structures and relative configurations of these compounds were established by the analysis of HRMS, 1D and 2D-NMR spectroscopy and the comparison with data in the literature. The compounds 2-6 were first isolated from Talaromyces genus. Herein, the chemotaxonomic significance of these compounds is described.