RISK OF EPILEPSY FOLLOWING FEBRILE CONVULSIONS
RISK OF EPILEPSY FOLLOWING FEBRILE CONVULSIONS
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DOI：
10.1212/wnl.29.3.297
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发表时间：
1979-01-01
期刊：
影响因子：
9.9
通讯作者：
KURLAND, LT
中科院分区：
文献类型：
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作者：
ANNEGERS, JF;HAUSER, WA;KURLAND, LT
研究人员对 666 名伴有发烧惊厥的儿童进行了跟踪调查，以确定随后发生癫痫的风险。患有脑瘫或智力低下的儿童存在高风险。其他主要危险因素是热性惊厥的非典型特征（例如局灶性惊厥）和热性惊厥持续时间为 10 分钟或更长时间。对于所有经历过热性惊厥的儿童来说，20 岁时患癫痫的风险约为 6%。该风险数字包括 2.5% 的儿童没有既往神经系统疾病或不典型或长期癫痫发作，以及 17% 的患有此类并发症的儿童。
A cohort of 666 children who had convulsions with fever were followed to determine the risks of subsequent epilepsy. High risks were found in children with preexisting cerebral palsy or mental retardation. Other major risk factors were atypical features of the febrile convulsions (such as focal seizures) and duration of febrile seizures for 10 min or more. The risk of developing epilepsy by age 20 was about 6% for all children who had experienced febrile convulsions. This risk figure consisted of a combination of 2.5% of children without prior neurologic disorder or atypical or prolonged seizures, and 17% of those with such complications.