ALTERATIONS OF SERUM-LIPIDS AND LIPOPROTEINS IN BREAST-CANCER
ALTERATIONS OF SERUM-LIPIDS AND LIPOPROTEINS IN BREAST-CANCER
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DOI：
10.1016/0304-3835(94)90008-6
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发表时间：
1994-07-29
期刊：
影响因子：
9.7
通讯作者：
BALOGLU, H
中科院分区：
文献类型：
--
作者：
KOKOGLU, E;KARAARSLAN, I;BALOGLU, H
对I期和IV期乳腺癌患者的血清甘油三酯、总胆固醇、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)和极低密度脂蛋白(VLDL)胆固醇水平进行定量，以评估疾病早期和晚期血清脂质和脂蛋白的变化。与年龄匹配的健康女性的数据相比，乳腺癌患者的空腹血清甘油三酯和极低密度脂蛋白胆固醇水平显着升高，而高密度脂蛋白胆固醇水平显着降低。此外，与 I 期乳腺癌患者相比，IV 期乳腺癌患者的甘油三酯和 VLDL 胆固醇显着增加，总胆固醇、HDL 和 LDL 胆固醇水平显着降低。 I 期乳腺癌患者和健康对照之间的总胆固醇和低密度脂蛋白胆固醇没有显着差异。
Serum triglycerides, total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very-low density lipoprotein (VLDL) cholesterol levels were quantified in Stage I and Stage IV breast cancer patients in order to evaluate the changes in serum lipids and lipoproteins in the early and advanced stages of the disease. When compared with data from age-matched healthy females, fasting serum triglycerides and VLDL cholesterol levels were found to be significantly increased and HDL cholesterol levels significantly decreased in patients with breast cancer. Furthermore, a significant increase in triglycerides and VLDL cholesterol and decreases in total, HDL and LDL cholesterol levels were demonstrated in patients with Stage IV disease when compared to those with Stage I breast cancer. No significant difference was found in total and LDL cholesterol between Stage I breast cancer patients and healthy controls.