ISOLATION OF MULTIPLE STRAINS OF CYTOMEGALOVIRUS FROM WOMEN ATTENDING A CLINIC FOR SEXUALLY-TRANSMITTED DISEASES
ISOLATION OF MULTIPLE STRAINS OF CYTOMEGALOVIRUS FROM WOMEN ATTENDING A CLINIC FOR SEXUALLY-TRANSMITTED DISEASES
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DOI：
10.1093/infdis/155.4.655
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发表时间：
1987-04-01
影响因子：
6.4
通讯作者：
MCDOUGALL, JK
中科院分区：
文献类型：
--
作者：
CHANDLER, SH;HANDSFIELD, HH;MCDOUGALL, JK
为了研究巨细胞病毒(CMV)外源性再感染的发生，我们检测了8名就诊性传播疾病(STD)诊所的女性和7名接受常规产前护理的女性的宫颈、尿液和喉部的系列分离株。用病毒DNA的限制性内切酶“指纹”法比较分离株。来自性病诊所的八名女性中有四人感染了一种以上的CMV毒株。两名女性在系列分离株中分离出不同的菌株，两名女性同时从不同的身体部位分离出不同的菌株。这些结果表明，在接触CMV的高概率女性中，外源性再感染并不少见。
To study the occurrence of exogenous reinfection with cytomegalovirus (CMV), we examined serial isolates from the cervix, urine, and throat of eight women attending a clinic for sexually transmitted diseases (STD) and seven women receiving routine prenatal care. Isolates were compared by restriction enzyme "fingerprinting" of viral DNA. Four of the eight women from the STD clinic were infected with more than one strain of CMV. Two women shed different strains in serial isolates, and two women shed different strains simultaneously from different body sites. These results suggest that exogenous reinfection is not uncommon in women with high probability of exposure to CMV.