Multiple-bandwidth photoacoustic tomography
Multiple-bandwidth photoacoustic tomography
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DOI：
10.1088/0031-9155/49/7/018
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发表时间：
2004-04-07
影响因子：
3.5
通讯作者：
Wang, LHV
中科院分区：
文献类型：
--
作者：
Ku, G;Wang, XD;Wang, LHV
光声层析成像，也被称为光声断层成像，利用短激光脉冲在生物组织中产生超声波。重建的图像可以通过样本结构、激光脉冲以及用于检测的超声换能器的脉冲响应的卷积来表征。尽管激光诱导的超声波覆盖很宽的频谱范围，但由于单个换能器带宽有限，它只能接收部分频谱。为了系统地分析这个问题，我们构建了一个光声层析成像系统，该系统同时使用多个超声换能器，每个换能器具有不同的中心频率。对与不同换能器相关的光声图像进行了比较和分析。通过对小鼠大脑和仿体样本成像对该系统进行了测试。所有换能器都能显示大脑中的血管，但图像分辨率不同。高频探测器提供了更好的图像分辨率，而低频探测器以更高的信噪比描绘出主要的结构特征。
Photoacoustic tomography, also referred to as optoacoustic tomography, employs short laser pulses to generate ultrasonic waves in biological tissues. The reconstructed images can be characterized by the convolution of the structure of samples, the laser pulse and the impulse response of the ultrasonic transducer used for detection. Although the laser-induced ultrasonic waves cover a wide spectral range, a single transducer can receive only part of the spectrum because of its limited bandwidth. To systematically analyse this problem, we constructed a photoacoustic tomographic system that uses multiple ultrasonic transducers simultaneously, each at a different central frequency. The photoacoustic images associated with the different transducers were compared and analysed. The system was tested by imaging both mouse brains and phantom samples. The vascular vessels in the brain were revealed by all of the transducers, but the image resolutions differed. The higher frequency detectors provided better image resolution while the lower frequency detectors delineated the major structural traits with a higher signal-noise ratio.