Methicillin-resistant Staphylococcus aureus (MRSA) infection in glomerulonephritis--a novel hazard emerging on the horizon.
Methicillin-resistant Staphylococcus aureus (MRSA) infection in glomerulonephritis--a novel hazard emerging on the horizon.
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肾小球肾炎中的耐甲氧西林金黄色葡萄球菌 (MRSA) 感染——一种即将出现的新危险。
DOI：
10.1093/ndt/13.12.2999
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
A. Koyama
中科院分区：
文献类型：
--
作者：
M. Kobayashi;A. Koyama
结论最近的研究在体内使用同位素和净平衡技术相结合，证实了早期的体外研究和动物实验中提供的证据，肾脏在正常的碳水化合物稳态和常见的病理情况下，如糖尿病和肾功能不全患者中发挥着重要作用。需要进一步的研究来检查（i）底物可用性、胰岛素和其他激素对肾脏葡萄糖代谢的调节，以及（ii）肾脏在禁食、酸中毒、运动、创伤和其他应激过程中对低血糖反调节和适应性变化的作用。
ConclusionsRecent studies in vivo using a combination of isotope and net balance techniques have corroborated earlier in vitro studies and animal experiments in providing evidence that the kidney plays an important role in normal carbohydrate homeostasis and under common pathologic situations such as in patients with diabetes mellitus and renal insufficiency. Further studies are needed to examine (i) regulation of renal glucose metabolism by substrate availability, insulin, and other hormones, and (ii) the contribution of the kidney to hypoglycaemia counterregulation and adaptive changes during fasting, acidosis, exercise, trauma, and other stresses associated with increased gluconeogenesis.